Job Description

Description

Be empowered to be innovative and creative where difference is valued Join a place built on innovation and creativity. Where different views and perspectives are welcomed and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve Who we are Naturally curious, we are forever connecting and collaborating. Uncovering new insights that equip us to challenge convention and push the boundaries. What we do Ultimately, our aim is to work towards a cure for some of the world’s most complex diseases. Whether that’s by shaping the patient ecosystem and focusing on outcomes, or by progressing potential medicines and accelerating their launch. Why we love it This is the place to make an impact. Here we ensure everyone can reach their full potential, perform at their best and make a valued contribution to the enterprise. The Respiratory and Immunology (R&I) Translational Science and Experimental Medicine (TSEM) department is an agile environment, with a culture that is science and patient-focused. Our mission is to understand disease mechanisms at the molecular level, identify the most effective target and the right patient population, and close the gap between bench science and bedside clinical practice. Within R&I, a new clinical imaging strategy has been established with the aim of developing and validating novel imaging techniques that can be employed in clinical trials to deliver life-changing medication. TSEM will be central in delivering this strategy and so we are expanding our experimental imaging team. The position of an Imaging Scientist is a key role, as they will play a central part in delivering the imaging strategy and for ensuring clinical robustness of experimental plans, developing novel imaging studies for respiratory and immunological diseases and analysing imaging data. This requires an individual with strong communication, imaging data analysis and computational skills as well as the ability to build strong relationships with stakeholders in TSEM, clinical development, and other functions within AstraZeneca, and to work effectively with external academic collaborators. Accountabilities and Responsibilities: • With the experiment imaging team and head of experimental imaging, implement the early R&I imaging strategy. • Design and deliver novel experimental imaging studies that provide critical insights into the role of clinical imaging in the development of novel respiratory and immunology therapeutics. • Develop and lead clinical imaging collaborations with key external partners that provide insights into disease mechanisms, patient selection, precision medicine strategies and clinical endpoints. • Perform/develop novel quantitative image analysis on imaging datasets using radiomic and/or AI approaches. • Provide scientific leadership in the field of imaging with innovative design, execution, and interpretation of experimental imaging trials. • Identify and work with image analysis companies to provide key experimental data. • Fully catalogue R&I legacy imaging studies, maximising imaging data acquisition and insights. • Maintains a high degree of understanding and awareness of new and emerging imaging modalities and techniques. • Works as member of Experimental Medicine Team to deliver departmental vision, strategy and goals • Makes AZ scientifically visible by publishing scientific papers and presenting data at conferences. Essential Requirements: • PhD in data science, computer science, physics or a related field or in life sciences with significant clinical imaging experience • At least 3 years experience of conducting radiological image-analysis based clinical research • Familiarity with image analysis software such as 3D Slicer, Matlab, ImageJ, Osirix, or Amira • Experience of analysing medical imaging data (e.g. CT, MRI) and familiarity with image formats (e.g. DICOM) • Expertise in at least one of the following; • Radiomic analytical approaches to medical imaging. • AI/ML approaches into medical image analysis. • Designing, implementing and interpreting experimental clinical imaging studies. • Programming using R, Python, C or similar to develop and build novel clinical image analysis platforms. • Ability to work productively and successfully in a matrix team environment with excellent collaborative skills. • Proven leadership ability & a self starter • Excellent written, oral, presentation and interpersonal skills. • Experience and understanding of biology, pharmacology, translational medicine and clinical sciences. • Track record of project delivery Desirable Requirements: • Imaging experience in the Respiratory or Immunology therapy area • 3 years of experience working in pharmaceutical R&D in discovery and development setting. At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. So, what’s next? Are you already imagining yourself joining us? Good, because we can’t wait to hear from you!